The address for the main entrance of the park is 15099 Cape Henlopen Dr, Lewes, DE 19958.

The address for the Biden Environmental Center is 37565 Dune Rd, Lewes, DE 19958.

Take Route 1 to Lewes. From Route 1 in Lewes, head northeast on Route 9 to Cape Henlopen Dr. Turn east (right) onto Cape Henlopen Dr which leads to the main entrance of the park. After the entrance booths, bear left around the bend and turn right on Dune Rd. Follow the signs for The Biden Center. It's about a half mile past Fort Miles on the left.

The Lewes Ferry Terminal from Cape May, New Jersey, is less than a mile to the park entrance. It's about a 2-minute drive.